Publications

2024

  • Winkelmann S, Lebahn K, Ezzat M, Schmitt K, Napp A, Oppel N, Pohl F, Kampmann A, Grabow N, Lenarz T, Paasche G. First in vivo test of a biodegradable polymeric stent for the Eustachian tube in sheep. Front. Audiol. Otol. 2024 2:1414831. doi: 10.3389/fauot.2024.1414831

  • Schmitt K, Timm M, Krüger P, Oppel N, Napp A, Pohl F, Schuon R, Kampmann A, Kötter L, Bankstahl M, Lenarz T, Stein T, Paasche G. Long-Term Preclinical Evaluation of a Permanent Stent Developed for the Human Eustachian Tube. Bioengineering (Basel). 2024 Jul 25;11(8):755. doi: 10.3390/bioengineering11080755

2023

  • Behrends W, Ahrens D, Bankstahl JP, Esser KH, Paasche G, Lenarz T, Scheper V. Refinement of systemic guinea pig deafening in hearing research: Sensorineural hearing loss induced by co-administration of kanamycin and furosemide via the leg veins. Lab Anim. 2023 Dec;57(6):631-641. doi: 10.1177/00236772231167679. Epub 2023 Apr 18.

  • Rosenbusch L, Schuon R, Wilfling T, Krüger P, Lebahn K, John S, Sahmel O, Grabow N, Schulze M, Wree A, Schmitz KP, Stein T, Lenarz T, Paasche G. Investigation of Stent Prototypes for the Eustachian Tube in Human Donor Bodies. Bioengineering (Basel). 2023 Jun 20;10(6):743. doi: 10.3390/bioengineering10060743.

  • Behrends W, Wulf K, Raggl S, Fröhlich M, Eickner T, Dohr D, Esser K-H, Lenarz T, Scheper V, Paasche G. Dual Drug Delivery in Cochlear Implants: In Vivo Study of Dexamethasone Combined with Diclofenac or Immunophilin Inhibitor MM284 in Guinea Pigs. Pharmaceutics 2023; 15:726. https://doi.org/10.3390/pharmaceutics15030726.

  • Goblet M, Lenarz T, Paasche G. Effect of Immunophilin Inhibitors on Cochlear Fibroblasts and Spiral Ganglion Cells. Audiol Neurootol. 2023;28(1):43-51. doi: 10.1159/000526454. Epub 2022 Sep 8.

2022

  • Oppel N, Paasche G, Bleich A, Lenarz T, Schuon R. Intravascular Ultrasonography (IVUS)-A Tool for Imaging the Eustachian Tube? Bioengineering (Basel). 2022 Nov 28;9(12):733. doi: 10.3390/bioengineering9120733.

  • Konrad S, Büchner A, Lenarz T, Paasche G. Impedance development after implantation of hybrid-L24 cochlear implant electrodes. Int J Audiol. 2022 Oct 4:1-8. doi: 10.1080/14992027.2022.2125914. Online ahead of print.

  • Oppel N, Ezzat M, Krüger P, Schmitt K, Napp A, Pohl F, Bleich A, Lenarz T, Stein T, Paasche G, Schuon R. Development of an In Vivo Model for Eustachian Tube Dysfunction. Bioengineering (Basel). 2022 Jul 15;9(7):317. doi: 10.3390/bioengineering9070317.

  • Anacker A, Esser KH, Lenarz T, Paasche G. Purification of Fibroblasts From the Spiral Ganglion. Front Neurol. 2022 Apr 15;13:877342. doi: 10.3389/fneur.2022.877342. eCollection 2022.

  • Wulf K, Goblet M, Raggl S, Teske M, Eickner T, Lenarz T, Grabow N, Paasche G. PLLA Coating of Active Implants for Dual Drug Release Molecules. 2022 Feb 19;27(4):1417. doi: 10.3390/molecules27041417.

2021

  • Schuon R, Schwarzensteiner J, Paasche G, Lenarz T, John S. Functional aspects of the Eustachian tube by means of 3D-modeling. PLoS One. 2021 Aug 12;16(8):e0244909. doi: 10.1371/journal.pone.0244909. eCollection 2021.

  • Goblet M, Matin F, Lenarz T, Paasche G. Optical absorbance of the tympanic membrane in rat and human samples. PLoS One. 2021 Jul 22;16(7):e0254902. doi: 10.1371/journal.pone.0254902. eCollection 2021.

2020

  • Scheper V, Seidel-Effenberg I, Lenarz T, Stöver T, Paasche G. Consecutive Treatment with Brain-Derived Neurotrophic Factor and Electrical Stimulation Has a Protective Effect on Primary Auditory Neurons. Brain Sci. 2020 Aug 15;10(8):559. doi: 10.3390/brainsci10080559.

  • Konrad S, Framke T, Kludt E, Büchner A, Lenarz T, Paasche G. Do Impedance Changes Correlate With a Delayed Hearing Loss After Hybrid L24 Implantation? Ear Hear. 2020 Aug 3;42(1):163-172. doi: 10.1097/AUD.0000000000000914.

  • Peter MN, Paasche G, Reich U, Lenarz T, Warnecke A. Differential Effects of Low- and High-Dose Dexamethasone on Electrically Induced Damage of the Cultured Organ of Corti. Neurotox Res. 2020 Aug;38(2):487-497. doi: 10.1007/s12640-020-00228-7. Epub 2020 Jun 3.

  • Janzen-Senn I, Schuon RA, Tavassol F, Lenarz T, Paasche G. Dimensions and position of the Eustachian tube in Humans. PLoS One. 2020 May 4;15(5):e0232655. doi: 10.1371/journal.pone.0232655. eCollection 2020.

2019

  • Schuon R, Mrevlje B, Vollmar B, Lenarz T, Paasche G. Intraluminal three-dimensional optical coherence tomography - a tool for imaging of the Eustachian tube?. J Laryngol Otol. 2019 Feb;133(2):87-94. doi: 10.1017/S002221511800230X. Epub 2019 Feb 18.

  • Peter MN, Warnecke A, Reich U, Olze H, Szczepek AJ, Lenarz T, Paasche G. Influence of In Vitro Electrical Stimulation on Survival of Spiral Ganglion Neurons. Neurotox Res. 2019 Jul;36(1):204-216. doi: 10.1007/s12640-019-00017-x. Epub 2019 Mar 7. Erratum in: Neurotox Res. 2019 Apr 4;:.

  • Peter MN, Paasche G, Reich U, Lenarz T, Warnecke A. [Reactions in the organ of Corti to electrical stimulation : StED technology for detecting changes]. HNO. 2019 Apr;67(4):251-257. doi: 10.1007/s00106-019-0641-7. Review. German.

2018

  • Pohl F, Schuon RA, Miller F, Kampmann A, Bültmann E, Hartmann C, Lenarz T, Paasche G. Stenting the Eustachian tube to treat chronic otitis media - a feasibility study in sheep. Head Face Med. 2018 May 4;14(1):8. doi: 10.1186/s13005-018-0165-5.

2017

  • Pohl F, Paasche G, Lenarz T, Schuon R. Tympanometric measurements in conscious sheep - a diagnostic tool for pre-clinical middle ear implant studies. Int J Audiol. 2017 Jan;56(1):53-61.

  • Dencker F, Dreyer L, Müller D, Zernetsch H, Paasche G, Sindelar R, Glasmacher B. A silicone fiber coating as approach for the reduction of fibroblast growth on implant electrodes. J Biomed Mater Res B Appl Biomater. 2017 Nov;105(8):2574-2580. doi: 10.1002/jbm.b.33798.

  • Miller F, Hinze U, Chichkov B, Leibold W, Lenarz T, Paasche G. Validation of eGFP fluorescence intensity for testing in vitro cytotoxicity according to ISO 10993-5. J Biomed Mater Res B Appl Biomater. 2017 May;105(4):715-722. doi: 10.1002/jbm.b.33602.

  • Schulze J, Kaiser O, Paasche G, Lamm H, Pich A, Hoffmann A, Lenarz T, Warnecke A. Effect of hyperbaric oxygen on BDNF-release and neuroprotection: Investigations with human mesenchymal stem cells and genetically modified NIH3T3 fibroblasts as putative cell therapeutics. PLoS One. 2017 May 23;12(5):e0178182. doi: 10.1371/journal.pone.0178182. eCollection 2017.

  • Scheper V, Hessler R, Hütten M, Wilk M, Jolly C, Lenarz T, Paasche G. Local inner ear application of dexamethasone in cochlear implant models is safe for auditory neurons and increases the neuroprotective effect of chronic electrical stimulation. PLoS One. 2017 Aug 31;12(8):e0183820. doi: 10.1371/journal.pone.0183820. eCollection 2017.

2016

2015

2014

2013

Before 2013

About The VIANNA research team