Publications

2017

• Roemer A, Staecker H, Sasse S, Lenarz T, Warnecke A. Biologische Therapien in der Otologie. HNO. 2017 Feb 15. doi: 10.1007/s00106-016-0304-x.

2016

• Roger Y, Schäck LM, Koroleva A, Noack S, Kurselis K, Krettek C, Chichkov B, Lenarz T, Warnecke A, Hoffmann A. Grid-like surface structures in thermoplastic polyurethane induce anti-inflammatory and anti-fibrotic processes in bone marrow-derived mesenchymal stem cells. Colloids Surf B Biointerfaces. 2016 Dec;148:104-115. doi: 10.1016/j.colsurfb.2016.06.024. Epub 2016 Jun 16.

• Roemer A, Köhl U, Majdani O, Klöß S, Falk C, Haumann S, Lenarz T, Kral A, Warnecke A. Biohybrid cochlear implants in human neurosensory restoration. Stem Cell Res Ther. 2016 Oct 7;7(1):148. doi: 10.1186/s13287-016-0408-y

• Schäck L, Budde S, Lenarz T, Krettek C, Gross G, Windhagen H, Hoffmann A, Warnecke A. Induction of neuronal-like phenotype in human mesenchymal stem cells by overexpression of Neurogenin1 and treatment with neurotrophins. Tissue Cell. 2016 Oct;48(5):524-32. doi: 10.1016/j.tice.2016.06.011. Epub 2016 Jun 27.

• Hadler C, Aliuos P, Brandes G, Warnecke A, Bohlmann J, Dempwolf W, Menzel H, Lenarz T, Reuter G, Wissel K2. Polymer Coatings of Cochlear Implant Electrode Surface - An Option for Improving Electrode-Nerve-Interface by Blocking Fibroblast Overgrowth. PLoS One. 2016 Jul;11(7):e0157710. doi: 10.1371/journal.pone.0157710. eCollection 2016.

• Burblies N, Schulze J, Schwarz HC, Kranz K, Motz D, Vogt C, Lenarz T, Warnecke A, Behrens P.Coatings of Different Carbon Nanotubes on Platinum Electrodes for Neuronal Devices: Preparation, Cytocompatibility and Interaction with Spiral Ganglion Cells. PLoS One. 2016 Jul;11(7):e0158571. doi: 10.1371/journal.pone.0158571. eCollection 2016.

• Lamm H, Müller-Kortkamp C, Warnecke A, Pohl F, Paasche G, Lenarz T, Stolle SR. Concurrent hyperbaric oxygen therapy and intratympanic steroid application as salvage therapy after severe sudden sensorineural hearing loss. Clin Case Rep. 2016 Feb;4(3):287-93. doi: 10.1002/ccr3.510. eCollection 2016.

• Aliuos P, Schulze J, Schomaker M, Reuter G, Stolle SR, Werner D, Ripken T, Lenarz T, Warnecke A.Magnetic Beads Enhance Adhesion of NIH 3T3 Fibroblasts: A Proof-of-Principle In Vitro Study for Implant-Mediated Long-Term Drug Delivery to the Inner Ear. PLoS One. 2016 Feb;11(2):e0150057. doi: 10.1371/journal.pone.0150057. eCollection 2016.

• Burke WF, Warnecke A, Schöner-Heinisch A, Lesinski-Schiedat A, Maier H, Lenarz T. Prevalence and audiological profiles of GJB2 mutations in a large collective of hearing impaired patients. Hear Res. 2016 Mar;333:77-86. doi: 10.1016/j.heares.2016.01.006. Epub 2016 Jan 15.

2015

• Schwieger J, Warnecke A, Lenarz T, Esser KH, Scheper V. Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination. PLoS One. 2015 Aug 11;10(8):e0133680. doi: 10.1371/journal.pone.0133680. eCollection 2015.

• Helmstaedter V, Tellkamp R, Majdani O, Warnecke A, Lenarz T, Durisin M. High-frequency jet ventilation for endolaryngotracheal surgery - chart review and procedure analysis from the surgeon’s and the anaesthesiologist’s point of view. Clin Otolaryngol. 2015 Aug;40(4):341-8. doi: 10.1111/coa.12376.

• Reich U, Warnecke A, Szczepek AJ, Mazurek B, Olze H. Establishment of an experimental system to study the influence of electrical field on cochlear structures. Neurosci Lett. 2015 Jul 10;599:38-42. doi: 10.1016/j.neulet.2015.05.027. Epub 2015 May 19.

• Durisin M, Büchner A, Lesinski-Schiedat A, Bartling S, Warnecke A, Lenarz T. Cochlear implantation in children with bacterial meningitic deafness: The influence of the degree of ossification and obliteration on impedance and charge of the implant. Cochlear Implants Int. 2015 May;16(3):147-58. doi: 10.1179/1754762814Y.0000000094. Epub 2014 Aug 17.

2014

• Wenzel GI, Sarnes P, Warnecke A, Stöver T, Jäger B, Lesinski-Schiedat A, Lenarz T. Non-penetrating round window electrode stimulation for tinnitus therapy followed by cochlear implantation. Eur Arch Otorhinolaryngol. 2014 Dec 6. doi: 10.1007/s00405-014-3413-8 [Epub ahead of print]

• Wrzeszcz A, Steffens M, Balster S, Warnecke A, Dittrich B, Lenarz T, Reuter G. Hydrogel coated and dexamethasone releasing cochlear implants: Quantification of fibrosis in guinea pigs and evaluation of insertion forces in a human cochlea model. J Biomed Mater Res B Appl Biomater. 2014 May 8. doi: 10.1002/jbm.b.33187. [Epub ahead of print]

• Kranz K, Warnecke A, Durisin M, Lenarz T, Scheper V. Phosphodiesterase type 4 inhibitor Rolipram improves survival of spiral ganglion neurons in vitro. Accepted February 2014 in PLOSone

• Kaiser O, Alious P, Wissel K, Lenarz T, Werner D, Reuter G, Kral A, Warnecke A. Dissociated neurons and glial cells derived from rat inferior colliculi after digestion with papain. PLoS One. 2013 Dec 12;8(12):e80490.

• Balster S, Wenzel GI, Warnecke A, Steffens M, Rettenmaier A, Zhang K, Lenarz T, Reuter G. Optical cochlear implant: evaluation of insertion forces of optical fibres in a cochlear model and of traumata in human temporal bones. Biomed Tech (Berl). 2014 Feb 1;59(1):19-28.

2013

• Kaiser O, Paasche G, Stöver T, Ernst S, Lenarz T, Kral A, Warnecke A. TGF-beta superfamily member activin A acts with BDNF and erythropoietin to improve survival of spiral ganglion neurons in vitro. Neuropharmacology. 2013 Aug 22;75C:416-425. doi: 10.1016/j.neuropharm.2013.08.008. [Epub ahead of print]

• Aliuos P, Sen A, Reich U, Dempwolf W, Warnecke A, Hadler C, Lenarz T, Menzel H, Reuter G. Inhibition of fibroblast adhesion by covalently immobilized protein repellent polymer coatings studied by single cell force spectroscopy. J Biomed Mater Res A. 2013 Apr 18. doi: 10.1002/jbm.a.34686. [Epub ahead of print]

• Alious P, Fadeeva E, Badar M, Winkel A, Mueller PP, Warnecke A, Chichkov B, Lenarz T, Reich U, Reuter G. Evaluation of single-cell force spectroscopy and microscopy to determine cell interactions with femtosecond-laser microstructured titanium surfaces. J Biomed Res Part A 2013;101(4):981-990.

Before 2013

• Warnecke A, Sasse S, Wenzel GI, Hoffmann A, Gross G, Paasche G, Scheper V, Reich U, Esser K-H, Lenarz T, Stöver T, Wissel K. Stable release of BDNF from the fibroblast cell line NIH3T3 grown on silicone elastomers enhances survival of spiral ganglion cells in vitro and in vivo. Hear Res. 2012 Jul;289(1-2):86-97.

• Reich U, Fadeeva E, Warnecke A, Paasche G, Mueller P, Chichkov B, Stöver T, Lenarz T, Reuter G. Directing neuronal cell growth on implant material surfaces by microstructuring. Journal of Biomedical Materials Research: Part B - Applied Biomaterials. 2012 May;100(4):940-947.

• Warnecke A, Scheper V, Buhr I, Wenzel GI, Wissel K, Paasche G, Berkingali N, Jørgensen JR, Lenarz T, Stöver T. Artemin improves survival of spiral ganglion neurons in vivo and in vitro. Neuroreport. 2010 May 12;21(7):517-21.

• Wenzel G, Warnecke A, Stöver T, Lenarz T. Effects of extracochlear gacyclidine perfusion on tinnitus in humans: a case series. Eur Arch Otorhinolaryngol. 2010 May;267(5):691-699.

• Kramer F, Stöver T, Warnecke A, Diensthuber M, Lenarz T, Wissel K. BDNF mRNA expression is significantly upregulated in vestibular schwannomas and correlates with proliferative activity. J Neurooncol. 2010 May;98(1):31-39.

• Warnecke A, Averbeck T, Soudah B, Wenzel GI, Lenarz T, Stöver T. Contact endoscopy for the evaluation of the pharyngeal and laryngeal mucosa. Laryngoscope. 2010 Feb;120(2):253-258.

• Scheper V, Paasche G, Miller JM, Warnecke A, Berkingali N, Lenarz T, Stöver T. Effects of delayed treatment with combined GDNF and continuous electrical stimulation on spiral ganglion cell survival in deafened guinea pigs. J Neurosci Res. 2009 May 1;87(6):1389-1399.

• Warnecke A, Luessen P, Sandmann J, Ikic M, Rossa S, Gutzki FM, Stichtenoth DO, Tsikas D. Application of a stable-isotope dilution technique to study the pharmacokinetics of human (15)N-labelled S-nitrosoalbumin in the rat: Possible mechanistic and biological implications. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 May;877(13):1375-1387.

• Berkingali N, Warnecke A, Gomes P, Paasche G, Tack J, Lenarz T, Stöver T. Neurite outgrowth on cultured spiral ganglion neurons induced by erythropoietin. Hear Res. 2008 Sep;243(1-2):121-126.

• Wissel K, Stöver T, Hofmann N-S, Chernajovsky Y, Daly G, Sasse S, Warnecke A, Lenarz T, Gross G, Hoffmann A. Fibroblast-mediated GDNF-delivery induces neuronal-like outgrowth in PC12 cells. Otol Neurotol. 2008 Jun;29(4):475-481.

• Torkos A, Wissel K, Warnecke A, Lenarz T, Stöver T. Technical report: Laser microdissection and pressure catapulting is superior to conventional manual dissection for isolating pure spiral ganglion fractions from the cochlea. Hear Res. 2008 Jan;235(1-2):8-14.

• Warnecke A, Wissel K, Hoffmann A, Hofmann N-S, Berkingali N, Groß G, Lenarz T, Stöver T. The biological effects of cell-delivered BDNF on cultured spiral ganglion cells Neuroreport. 2007 Oct;18(16)1683-1686.

• Lesinski-Schiedat A, Illg A, Warnecke A, Heerman R, Bertram B, Lenarz T. Kochleaimplantation bei Kindern im 1. Lebensjahr. Vorläufige Ergebnisse. HNO. 2005 Jul;54(7):565-572.

• Warnecke A, Averbeck T, Wurster U, Harmening M, Lenarz T, Stöver T. Diagnostic Relevance of β2-Transferrin for the Detection of Cerebrospinal Fluid Fistulas. Arch Otolaryngol, Head Neck Surg. 2004 Oct;130(10):1178-1184.

• Savva A, Taylor M, Beatty CW. Management of Cerebrospinal Fluid Leaks Involving the Temporal Bone: Report on 92 Patients. Laryngoscope 2003 Jan;113(1):50-56.

• Strome SE, Savva A, Brisset AE, Gostout BS, Lewis J, Clayton AC, McGovern R, Weaver AE, Persing D, Kasperbauer JL. Squamous cell carcinoma of the tonsils: a molecular analysis of HPV associations. Clin Cancer Res. 2002 Apr;8(4):1093-1100.

• Khabie N, Savva A, Kasperbauer JL, McGovern R, Gostout B, Strome SE. Epstein-Barr Virus DNA is not increased in Tonsillar Carcinoma. Laryngoscope. 2001 May;111(5):811-814.

• Tsikas D, Sandmann J, Lueßen P, Savva A, Rossa S, Stichtenoth DO, Frölich JC. S-Transnitrosylation of albumin in human plasma and blood in vitro and in vivo in the rat. Biochem Biophys. 2001 Apr;1546(2):422-434.

• Tsikas D, Sandmann J, Savva A, Lueßen P, Böger RH, Gutzki F-M, Mayer B, Frölich JC. Assessment of nitric oxide synthase activity in vitro and in vivo by gas chromatography-mass spectrometry. J Chrom B. 2000 May;742(1):143-153.